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Wisteria - knots and rot

Hi there

Just bought a house with an amazing wisteria covered pergola in the garden.  During pruning in winter it exposed massive knots/warty lumps and also some areas of rotting. Are these life threatening to the plant?  Should they be cut out?  We also found an old saw mark close to one of the areas and wonder if this is something that the previous owner may have done to tackle the rot and lumps.  Any advice gratefully received.  Many thanks

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